Tamoxifen Citrate

Tamoxifen Citrate is commonly sold under brand names such as Nolvadex and Soltamox.
Tamoxifen Citrate is a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of hormone receptor-positive breast cancer, particularly in premenopausal and postmenopausal women. It works by blocking estrogen receptors in breast tissue, thereby inhibiting the growth of estrogen-dependent tumors. Tamoxifen is also used in some cases to reduce the risk of breast cancer in women with a family history of the disease or those who have had certain types of benign breast conditions.

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Name

Type

Strength

Manufacturer

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Tamoxi

Tablet

20mg

Beacon Pharmaceuticals

Tamona

Tablet

20mg

Beximco Pharmaceuticals

Directions

  • Take tamoxifen citrate exactly as prescribed by your healthcare provider, typically once or twice daily, with or without food.
  • Swallow the tablet whole with a glass of water; do not crush or chew it.
  • Continue taking tamoxifen for the full duration prescribed by your doctor, even if you feel well, to ensure effective treatment.
  • If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.

Special Precautions

  • Inform your doctor if you have a history of blood clots, stroke, liver disease, or uterine cancer before starting tamoxifen citrate.
  • Women who are pregnant or breastfeeding should not take tamoxifen, as it may harm the fetus or infant.
  • Regular monitoring may be required to check for any potential side effects, including changes in liver function and signs of endometrial cancer.
  • Discuss any other medications or supplements you are taking with your healthcare provider, as tamoxifen can interact with certain drugs, including anticoagulants and some antidepressants.

Side Effects

Common side effects of tamoxifen citrate may include:

  • Hot flashes
  • Nausea
  • Fatigue
  • Vaginal discharge or bleeding
  • Changes in menstrual cycle

Serious side effects are less common but may include blood clots (indicated by swelling or pain in the legs), stroke symptoms (such as sudden numbness or weakness), and signs of liver problems (such as jaundice). Seek immediate medical attention if you experience any severe symptoms.

Missed Dosage

If you miss a dose of tamoxifen citrate, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses to make up for the missed one.

Storage Requirements

  • Store tamoxifen citrate at room temperature, between 68°F and 77°F (20°C to 25°C), away from moisture and direct sunlight.
  • Keep the medication in its original container, tightly closed when not in use.
  • Keep out of reach of children and pets.
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